Does Combined Spinal Epidural Anesthesia Decrease the Morbidity of Iliac Block Bone Grafting for Deficient Alveolar Ridges Compared With General Anesthesia?

Purpose: To evaluate the morbidity of iliac block bone grafting performed under general anesthesia (GA) or combined spinal epidural anesthesia (CSEA)

Intra-articular injection of dexketoprofen in rat knee joint : Histopathologic assessment of cartilage & synovium

Background & objectives: Effective pain control following outpatient surgical procedures is an important aspect of patient discharge. This study was carried out with an aim to investigate the histopathological effects of intra-articular dexketoprofen trometamol injection in knee joint on synovium and cartilage in an experimental rat model. Methods: In each of 40 rats, the right knee was designated as the study group and the left knee as the control group (NS group). Under aseptic conditions, 35 rats received an injection of 0.25 ml (6.25 mg) dexketoprofen trometamol into the right knee joint and an injection of 0.25 ml 0.9 per cent normal saline solution into the left knee joint. On the 1 st , 2 nd , 7 th , 14 th , and 21 st days after intra-articular injection, rats in specified groups were sacrificed by intraperitoneal injection of 120 mg/kg sodium thiopental. Knee joints were separated and sectioned for histopathological examination. Inflammatory changes in the joints were recorded according to a grade scale. Results: No significant difference in terms of pathological changes both in synovium and cartilage was observed between the NS group and the study group on days 1, 2, 7, 14 and 21 after intra-articular injection of dexketoprofen or saline in the knee joint. Interpretation & conclusions: The findings showed no evidence of significant histopathological damage to the cartilage and synovia for a period up to 21 days following intra-articular administration of dexketoprofen trometamol in the knee joints of rats

Leriche syndrome

Leriche syndrome is a disease that is characterized by a thrombotic occlusion in the aorta, frequently in the renal artery distal. The classical symptoms of this syndrome include pain in the lower extremities emerging during activity (claudication), impalpability of the femoral pulses and impotency in male patients. The definitive diagnosis of claudication, due to insufficient circulation as well as neurogenic-caused claudication, is hard. Medical history, physical examination and monitoring methods are important for definitive diagnosis. Impalpability of bilateral femoral pulses in physical examination may be a sign of leriche syndrome. With colored doppler ultrasonography, it can be demonstrated in cases having Leriche syndrome that there is no circulation in both iliac arteries. In these patients, thrombotic occlusion of the aorta shall be confirmed by computed tomography angiography. This case that we present is a case of Leriche syndrome in which the patient came to the hospital with the complaint of claudication and was diagnosed with lumbar disc herniation. Since vascular pathologies were not considered in definitive diagnosis, the treatment was delayed and it resulted in mortality; for this reason it is important. In the case of patients coming to hospital with complaints of leg pain, the vascular pathologies shall be thought of in the definitive diagnosis and the clinicians, and in that way leading to the diagnosis, shall depend on detailed patient history and comprehensive physical examination

Frank-ter Haar syndrome-additional findings?

Frank-ter Haar syndrome is a genetic disease that is transmitted by autosomal recessive pattern with characteristic features such as megalocornea or glaucoma, a prominent coccyx, heart defects, developmental delays, brachycephaly, a wide anterior fontanel, finger flexion deformities, full cheeks and micrognathia. Dentomaxillofacial features of this syndrome are not well documented in the literature. We present of a 21-year-old male with Frank-ter Haar syndrome and some features that may be linked with this syndrome not reported before in the literature

Intra-articular injection of dexketoprofen in rat knee joint : Histopathologic assessment of cartilage & synovium

Background objectives: Effective pain control following outpatient surgical procedures is an important aspect of patient discharge. This study was carried out with an aim to investigate the histopathological effects of intra-articular dexketoprofen trometamol injection in knee joint on synovium and cartilage in an experimental rat model